Anthrax Research Today is a free monthly online journal that collates and summarizes the latest research about Anthrax, including details on bacillus anthracis, contagiousness, exposure, effects.

Evaluation of immune response to orally administered Sterne strain 34F2 anthrax vaccine.

Shakya KP, Hugh-Jones ME, Elzer PH

Louisiana State University, School of Veterinary Medicine, Department of Pathobiological Sciences, Skip Bertman Dr., Baton Rouge, LA 70803, United States.

Present animal vaccines against Bacillus anthracis infection are capable of inducing protective immunity. However, due to the route of administration, the vaccine has limited or no use in wildlife especially in rural areas of the world. Hence, an oral vaccine is needed for controlling this disease. For proof of concept we used the commercially available Sterne strain 34F2 vaccine mixed with oral scarifying agents. Although the immunological response as measured by ELISA in this group was not equal to the parenterally inoculated animals, the results indicate that the oral administration of this vaccine with oropharyngeal mucosa scarifying agents mixed with feed can induce immune responses in goats.

Published 2 July 2007 in Vaccine, 25(29): 5374-7.
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